Predavanje: RELATIVE SURVIVAL: UNDERSTANDING THE CONCEPTS AND USING THE METHOD PDF natisni

Naslednje predavanje v okviru biostatističnega centra bo 14. oktobra 2008 na IBMI. Predaval bo prof.dr. Jacques Estève z Lyona.

RELATIVE SURVIVAL: UNDERSTANDING THE CONCEPTS AND USING THE METHOD

Relative survival methodology has a long history, which dates back to the 1950's. Its primary objective was to judge in a standardised manner the therapeutic progress, freed from the subjective determination of the cause of death of the patients. The pioneers of the methodology had clearly in mind the estimation of the net survival. For many years the methodology was based on the computation of the life table expected survival. This methodology has been used up to now by the cancer registries for the evaluation of the survival of the incident cancer patients.

In parallel important advances was made in the study of the statistics of stochastic processes and in modelling survival with multivariate regression. It was natural to try to model relative survival in the same way and much progress has been made in that respect.

This seminar will discuss the basic concept of net and relative survival and will retrace the evolution of the methodology. It will be illustrated with several examples showing the flexibility of the new methodology.

In practice the new tools are not widely used by cancer registries, despite their advantages over the classical estimates based on the computation of expected survival. It is likely that the lack of easy-to-use procedure within the more commonly used statistical software is responsible for this anomaly. The example of the "relsurv" R-package developed by Pohar et al should be followed by the development of similar tool for commercially available statistical software.